Partial splenic artery embolization for treatment of Hypersplenism in portal hypertension: Experience from tertiary referral centre

Background and Aim: Hypersplenism is a complication of portal hypertension commonly encountered in gastroenterology practice. Partial splenic artery embolization (PSAE) one the attractive treatment modalities, which less invasive than splenectomy for managing hypersplenism. We aimed to evaluate safety efficacy PSAE treating hypersplenism hypertension. Methods: analyzed prospectively collected data patients who underwent from January 2022 December followed them periodically. Demography, etiology hypertension, baseline hemogram presence aneurysm was noted. Primary outcome measures were improvement hematological parameters (red blood cell counts, white platelet counts) clinical (need transfusion). Secondary included complications related procedures. Results: Total 11 reviewed. Females 7 (63.6%). Mean age 34.6 years. Extrahepatic vein obstruction non-cirrhotic fibrosis as present 5 (45.5%) 3 (27.3%) cases respectively. Three cirrhotic (HBV: 2 cases, NASH: 1 case) all CTP-A. Concomitant cases. Technical success achieved 100% spleen size 20.5 cm, reduced by 1-2 cm post procedure majority Post embolization, RBCs, WBCs counts significantly improved at 4 weeks, 12 weeks 24 follow up (p-value <0.05) with no requirement product transfusion any patient. syndrome (fever, pain nausea/vomiting) manifested managed conservatively. One patient developed transient ascites spontaneous bacterial peritonitis, subsequently resolved. abscess sepsis ultimately died splenectomy. Conclusion: safe effective good short-term outcomes.